P100 wave latency in anisometropic and esotropic amblyopia versus normal eyes

Hosseinmenni, S. and Talebnejad, M. and Jafarzadehpur, E. and Mirzajani, A. and Osroosh, E. (2015) P100 wave latency in anisometropic and esotropic amblyopia versus normal eyes. Journal of Ophthalmic and Vision Research, 10 (3). pp. 268-273.

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Purpose: To evaluate cortical activity using pattern visual evoked potentials (PVEPs) in patients with mild and moderate amblyopia (esotropic and anisometropic). Methods: PVEP was recorded in 43 unilateral amblyopic patients, including 15 esotropic (ET) and 28 anisometropic (AM) patients, selected from three different medical centers in the city of Shiraz, Iran and compared to that obtained from 15 age and sex matched normal subjects who served as controls. Visual acuity (VA) in amblyopic eyes was equal to or less than 0.7 LogMAR. The latency of P100 was recorded monocularly using two check sizes of 15 and 60 min of arcs at two different levels of contrasts (30 and 100). Results: P100 latency in amblyopic eyes was significantly increased compared to the normal group (P < 0.001). There was a significant difference (P < 0.001) in P100 latency in anisometropic and esotropic amblyopic eyes as compared to normal subjects, using high spatial frequency and with both levels of contrast. A significant difference was observed with large check sizes and high contrast between anisometropic amblyopic and normal eyes (P = 0.03). However, there was no significant difference between these two groups and the control group with other stimuli. Conclusion: The neural response based on p100 latency in PVEP was different between amblyopic groups and normal subjects. PVEP may be valuable for diagnosis, prognosis and treatment of amblyopia. © 2015 Journal of Ophthalmic and Vision Research | Published by Wolters Kluwer - Medknow.

Item Type: Article
Additional Information: Cited By :2 Export Date: 16 February 2020 Correspondence Address: Jafarzadehpur, E.; Department of Optometry, Iran University of Medical Sciences, Shahnazari St., Iran; email: Jafarzadehpour.e@iums.ac.ir
Uncontrolled Keywords: Amblyopic Anisometropic Esotropic Visual Evoked Potential
Subjects: WW Ophthalmology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 11 May 2020 07:53
Last Modified: 11 May 2020 07:53
URI: http://eprints.mums.ac.ir/id/eprint/18902

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