Anesthetic keratopathy presenting as bilateral Mooren-like ulcers

Khakshoor, H. and Moshirfar, M. and Simpson, R. G. and Gharaee, H. and Vejdani, A. H. and Christiansen, S. M. and Edmonds, J. N. and Behunin, N. L. (2012) Anesthetic keratopathy presenting as bilateral Mooren-like ulcers. Clinical Ophthalmology, 6 (1). pp. 1719-1722.

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This observational case report describes the development of bilateral Mooren-like ulcers in a patient with anesthetic keratopathy. A 42-year-old man with a recent history of minor eye trauma and pain self-treated with tetracaine eye drops presented with complaints of acutely worsening vision and severe pain bilaterally. His visual acuity at presentation was limited to hand motion. Slit-lamp examination revealed bilateral epithelial defects at the center of the cornea, and an area of stromal infiltration and thinning with an undermining leading edge resembling a Mooren's ulcer in both eyes. Corneal haze and hypopyon were visible. Anesthetic use was halted immediately and the patient was started on prednisolone and mycophenolate mofetil (Cellcept®), after which visual acuity gradually improved and pain decreased. Despite improvement of symptoms, residual epithelial defects remained, and the patient was ultimately treated with keratoplasty for recovery of vision. We suggest that anesthetic keratopathy should be included in the differential diagnosis for any patient presenting with ring-shaped stromal infiltrates or nonhealing epithelial defects. © 2012 Simpson et al.

Item Type: Article
Additional Information: Cited By :4 Export Date: 16 February 2020 Correspondence Address: Moshirfar, M.65 Mario Capechi Drive, Salt Lake City, UT 84132, United States; email:
Uncontrolled Keywords: Anesthetic abuse Corneal damage Corneal ulceration amikacin cefazolin eye drops hydroxypropylmethylcellulose mycophenolic acid 2 morpholinoethyl ester prednisolone prednisone adult anesthesia induction article bacterial keratitis case report cornea rodent ulcer differential diagnosis disease exacerbation disease severity eye edema eye injury eye pain human keratopathy keratoplasty male medical history outcome assessment patient assessment self care slit lamp visual acuity visual impairment
Subjects: WW Ophthalmology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 13 May 2020 07:36
Last Modified: 13 May 2020 07:36

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