The Protective Effects of Nigella sativa and Its Constituents on Induced Neurotoxicity

Khazdair, M. R. (2015) The Protective Effects of Nigella sativa and Its Constituents on Induced Neurotoxicity. Journal of Toxicology, 2015.

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Abstract

Nigella sativa (N. sativa) is an annual plant and widely used as medicinal plant throughout the world. The seeds of the plant have been used traditionally in various disorders and as a spice to ranges of Persian foods. N. sativa has therapeutic effects on tracheal responsiveness (TR) and lung inflammation on induced toxicity by Sulfur mustard. N. sativa has been widely used in treatment of various nervous system disorders such as Alzheimer disease, epilepsy, and neurotoxicity. Most of the therapeutic properties of this plant are due to the presence of some phenolic compounds especially thymoquinone (TQ), which is major bioactive component of the essential oil. The present review is an effort to provide a comprehensive study of the literature on scientific researches of pharmacological activities of the seeds of this plant on induced neurotoxicity. © 2015 Mohammad Reza Khazdair.

Item Type: Article
Additional Information: Cited By :23 Export Date: 16 February 2020 Correspondence Address: Khazdair, M.R.; Pharmaceutical Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical SciencesIran; email: m.khazdair@yahoo.com
Uncontrolled Keywords: carvacrol central nervous system agents Nigella sativa extract thymoquinone Alzheimer disease anticonvulsant activity antioxidant activity black cumin brain protection clinical trial (topic) degenerative disease drug efficacy epilepsy human memory disorder neurotoxicity nonhuman Parkinson disease priority journal Review
Subjects: QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 13 May 2020 07:00
Last Modified: 13 May 2020 07:00
URI: http://eprints.mums.ac.ir/id/eprint/18925

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