Comparison of non-electrophoresis grade with electrophoresis grade BIS in NIPAM polymer gel preparation

Khodadadi, R. and Khajeali, A. and Farajollahi, A. R. and Hajalioghli, P. and Raeisi, N. (2015) Comparison of non-electrophoresis grade with electrophoresis grade BIS in NIPAM polymer gel preparation. BioImpacts, 5 (3). pp. 129-133.

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Introduction: The main objective of this study was to investigate the possibility of replacing electrophoresis cross-linker with non-electrophoresis N, N'-methylenebisacrylamide (BIS) in N-isopropyl acrylamide (NIPAM) polymer gel and its possible effect on dose response. Methods: NIPAM polymer gel was prepared from non-electrophoresis grade BIS and the relaxation rate (R2) was measured by MR imaging after exposing the gel to gamma radiation from Co-60 source. To compare the response of this gel with the one that contains electrophoresis grade BIS, two sets of NIPAM gel were prepared using electrophoresis and non-electrophoresis BIS and irradiated to different gamma doses. Results: It was found that the dose-response of NIPAM gel made from the non-electrophoresis grade BIS is coincident with that of electrophoresis grade BIS. Conclusion: Taken all, it can be concluded that the non-electrophoresis grade BIS not only is a suitable alternative for the electrophoresis grade BIS but also reduces the cost of gel due to its lower price. © 2015 The Author(s).

Item Type: Article
Additional Information: Cited By :2 Export Date: 16 February 2020 Correspondence Address: Farajollahi, A.R.; Medical Education Research CenterIran
Uncontrolled Keywords: Cross linker agent N, N'-Methylenebisacrylamide (BIS) NIPAM gel Polymer gel dosimetry n,n' methylenebisacrylamide poly(n isopropylacrylamide) Article cobalt therapy comparative study electrophoresis gamma radiation gel irradiation nuclear magnetic resonance imaging nuclear magnetic resonance scanner radiation dose
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 14 May 2020 16:55
Last Modified: 14 May 2020 16:55

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