Effects of a Topical Saffron (Crocus sativus L) Gel on Erectile Dysfunction in Diabetics: A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Trial

Mohammadzadeh-Moghadam, H. and Nazari, S. M. and Shamsa, A. and Kamalinejad, M. and Esmaeeli, H. and Asadpour, A. A. and Khajavi, A. (2015) Effects of a Topical Saffron (Crocus sativus L) Gel on Erectile Dysfunction in Diabetics: A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Trial. Journal of Evidence-Based Complementary and Alternative Medicine, 20 (4). pp. 283-286.

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Abstract

Erectile dysfunction is a man’s persistent or recurrent inability to achieve and maintain erection for a satisfactory sexual relationship. As diabetes is a major risk factor for erectile dysfunction, the prevalence of erectile dysfunction among diabetic men has been reported as 35 to 90. This randomized, parallel-group, double-blind, placebo-controlled trial investigated the effects of a topical saffron (Crocus sativus L) gel on erectile dysfunction in diabetic men. Patients were randomly allocated to 2 equal groups (with 25 patients each). The intervention group was treated with topical saffron, and the control received a similar treatment with placebo. The 2 groups were assessed using the International Index of Erectile Function Questionnaire before the intervention and 1 month after the intervention. Compared to placebo, the prepared saffron gel could significantly improve erectile dysfunction in diabetic patients (P <.001). This preliminary evidence suggests that saffron can be considered as a treatment option for diabetic men with erectile dysfunction. © 2015, The Author(s) 2015.

Item Type: Article
Additional Information: Cited By :3 Export Date: 16 February 2020 Correspondence Address: Nazari, S.M.; Department of Iranian Traditional Medicine, School of Traditional Medicine, Mashhad University of Medical SciencesIran
Uncontrolled Keywords: Crocus Sativus L diabetes erectile dysfunction saffron gel plant extract administration and dosage adult aged chemistry controlled study Crocus Diabetes Complications double blind procedure human male middle aged pathophysiology phytotherapy randomized controlled trial Double-Blind Method Gels Humans Plant Extracts
Subjects: QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 05 May 2020 05:51
Last Modified: 05 May 2020 05:51
URI: http://eprints.mums.ac.ir/id/eprint/18983

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