Evaluation of 101Rh as a brachytherapy source

Pakravan, D. and Ghorbani, M. and Meigooni, A. S. (2015) Evaluation of 101Rh as a brachytherapy source. Journal of Contemporary Brachytherapy, 7 (2).

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Purpose: Recently a number of hypothetical sources have been proposed and evaluated for use in brachytherapy. In the present study, a hypothetical 101Rh source with mean photon energy of 121.5 keV and half-life of 3.3 years, has been evaluated as an alternative to the existing high-dose-rate (HDR) sources. Dosimetric characteristics of this source model have been determined following the recommendation of the Task Group 43 (TG-43) of the American Association of the Physicist in Medicine (AAPM), and the results are compared with the published data for 57Co source and Flexisource 192Ir sources with similar geometries. Material and methods: MCNPX Monte Carlo code was used for simulation of the 101Rh hypothetical HDR source design. Geometric design of this hypothetical source was considered to be similar to that of Flexisource 192Ir source. Task group No. 43 dosimetric parameters, including air kerma strength per mCi, dose rate constant, radial dose function, and two dimensional (2D) anisotropy functions were calculated for the 101Rh source through simulations. Results: Air kerma strength per activity and dose rate constant for the hypothetical 101Rh source were 1.09 ± 0.01 U/mCi and 1.18 ± 0.08 cGy/(h.U), respectively. At distances beyond 1.0 cm in phantom, radial dose function for the hypothetical 101Rh source is higher than that of 192Ir. It has also similar 2D anisotropy functions to the Flexisource 192Ir source. Conclusions: 101Rh is proposed as an alternative to the existing HDR sources for use in brachytherapy. This source provides medium energy photons, relatively long half-life, higher dose rate constant and radial dose function, and similar 2D anisotropy function to the Flexisource 192Ir HDR source design. The longer half-life of the source reduces the frequency of the source exchange for the clinical environment. © 2015, Termedia Publishing House Ltd. All rights reserved.

Item Type: Article
Additional Information: Cited By :4 Export Date: 16 February 2020 Correspondence Address: Pakravan, D.; Department of Physics, Ahvaz Branch, Islamic Azad University, Golestan Blvd., Farhang Shahr, PO Box: 61349-37333, Iran; email: pakravan@iauahvaz.ac.ir
Uncontrolled Keywords: 101Rh Brachytherapy Hypothetical source TG-43 dosimetric parameters cobalt 57 iridium 192 radioisotope rhodium 101 unclassified drug anisotropy Article half life time Monte Carlo method photon radiation dose rate constant
Subjects: WN Radiology . Diagnostic Imaging
QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 05 May 2020 08:35
Last Modified: 05 May 2020 08:35
URI: http://eprints.mums.ac.ir/id/eprint/19026

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