Demonstration of focal physiologic in-vivo somatostatin receptor expression in the caput epididymis of the testes on 68Ga-DOTANOC PET/CT and 177Lu-DOTATATE post-therapy whole body scintigraphy

Parihar, Ashwin and Sood, Apurva and Sood, Ashwani and Gulati, Ajay and Mittal, Bhagwant (2020) Demonstration of focal physiologic in-vivo somatostatin receptor expression in the caput epididymis of the testes on 68Ga-DOTANOC PET/CT and 177Lu-DOTATATE post-therapy whole body scintigraphy. Asia Oceania Journal of Nuclear Medicine and Biology, 8 (2). pp. 132-135.

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Abstract

We present the case of a 60-year-old man with metastatic neuroendocrine tumor of the ileum following ileal resection, being evaluated for 177Lu-based peptide receptor radionuclide therapy. 68Ga-DOTANOC PET/CT showed focal increased tracer uptake in the scrotal region without any morphologic changes on the corresponding CT images. Similar increased tracer uptake was seen on post-therapy whole-body imaging following 177Lu-DOTATATE therapy. An USG guided FNA revealed no malignant cells on cytopathologic examination. This case illustrates that focal testicular tracer uptake, may not always be pathological and can represent a normal physiologic variant, similar to the diffuse testicular somatostatin receptor expression as previously reported in literature.

Item Type: Article
Uncontrolled Keywords: 68Ga-DOTANOC- PET/CT,Testicular uptake,Physiologic Neuroendocrine tumor,177Lu-DOTATATE,Somatostatin receptor,DOTATOC
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Journals > Asia Oceania J Nuclear Medicine & Biology
Depositing User: AOJNMB AOJNMB
Date Deposited: 27 Jun 2020 08:49
Last Modified: 27 Jun 2020 08:49
URI: http://eprints.mums.ac.ir/id/eprint/19470

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