The role of FDG PET/CT in the evaluation of treatment response in a case of calcified ovarian metastases

Saidi, Bahare and Fallahi, Babak and Eftekhari, Mohammad and Ghorbani, Mahsa and Fard-Esfahani, Armaghan (2020) The role of FDG PET/CT in the evaluation of treatment response in a case of calcified ovarian metastases. Asia Oceania Journal of Nuclear Medicine and Biology, 8 (2). pp. 145-148.

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Evaluation of calcified metastatic lesions by conventional imaging can be challenging. Ovarian cancer metastases can present with calcification which might increase in size and number following therapy. It is not entirely clear whether these calcifications are associated with tumor response or disease progression. Calcified lesions which do not change in size or configuration are particularly problematic when assessed by RECIST criteria. Positron emission tomography (PET)/computed tomography (CT) is of particular value as it demonstrates the metabolic activity of the calcified lesions, in addition, it might reveal metastases in unexpected sites. We report a case of serous papillary ovarian cancer with extensive abdomino-pelvic calcified metastases referred for evaluation of therapy response. Despite being reported as stable disease on CT evaluation, we observed increased metabolic activity in the calcified lesions both on CT-attenuation corrected and non-attenuation corrected images, which was indicative of inadequate response to therapy. PET/CT is an ideal modality in follow-up of patients with ovarian cancer presenting with calcified metastatic tumoral deposits.

Item Type: Article
Uncontrolled Keywords: Calcified metastases,Ovary cancer,PET/CT
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Journals > Asia Oceania J Nuclear Medicine & Biology
Depositing User: AOJNMB AOJNMB
Date Deposited: 27 Jun 2020 08:51
Last Modified: 27 Jun 2020 08:51

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