Saffron supplements modulate serum pro-oxidant-antioxidant balance in patients with metabolic syndrome: A randomized, placebo-controlled clinical trial

Kermani, Tayyebeh and Mousavi, Seyyed Hadi and Shemshian, Maryam and Norouzy, Abdolreza and Mazidi, Mohsen and Moezzi, Atefeh and Moghiman, Toktam and Ghayour-Mobarhan, Majid and Ferns, Gordon. A. (2015) Saffron supplements modulate serum pro-oxidant-antioxidant balance in patients with metabolic syndrome: A randomized, placebo-controlled clinical trial. Avicenna Journal of Phytomedicine, 5 (5). pp. 427-433.

[img]
Preview
Text
AJP_Volume 5_Issue 5_Pages 427-433.pdf

Download (576kB) | Preview
Official URL: http://ajp.mums.ac.ir/article_4672.html

Abstract

Objectives: We have investigated the effect of a saffron supplement, given at a dose of 100 mg/kg, on prooxidant-antioxidant balance (PAB) in individuals with metabolic syndrome. Materials and Methods: A randomized, placebo-controlled trial design was used in 75 subjects with metabolic syndrome who were randomly allocated to one of two study groups: (1) the case group received 100mg/kg saffron and (2) the placebo control group received placebo for 12 weeks. The serum PAB assay was applied to all subjects before (week 0) and after (weeks 6 and 12) the intervention. Results: There was a significant (p=0.035) reduction in serum PAB between week 0 to week 6 and also from week 0 to week 12. Conclusion: Saffron supplements can modulate serum PAB in subjects with metabolic syndrome, implying an improvement in some aspects of oxidative stress or antioxidant protection.

Item Type: Article
Subjects: QU Biochemistry
W General medicine- Health professions
Divisions: Journals > Avicenna J Phytomedicine
Depositing User: ajp ajp
Date Deposited: 21 Sep 2017 13:10
Last Modified: 21 Sep 2017 13:10
URI: http://eprints.mums.ac.ir/id/eprint/2021

Actions (login required)

View Item View Item