An Unusual Presentation of Granulomatosis with Polyangiitis

Sodhi, Rakhee and Khanduri, Sushant and Jethani, Varuna and Nadia, Shirazi and Kumar, Manoj (2017) An Unusual Presentation of Granulomatosis with Polyangiitis. Journal of Cardio-Thoracic Medicine, 5 (3). pp. 204-207.

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Abstract

The granulomatosis with polyangiitis (GPA), formerly known as Wegener�s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN). The antinuclear (ANA) and anti-neutrophil cytoplasmic antibodies (ANCA) are considered as relatively specific markers of the disease. Herein, we presented the case of a patient who initially presented with sepsis but did not respond to the conventional antibiotics and later diagnosed with GPA.The granulomatosis with polyangiitis (GPA), formerly known as Wegener�s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN).The antinuclear (ANA) and anti-neutrophil cytoplasmic antibodies (ANCA) are considered as relatively specific markers of the disease. Herein, we presented the case of a patient who initially presented with sepsis but did not respond to the conventional antibiotics and later diagnosed with GPA.

Item Type: Article
Subjects: WO Surgery
Divisions: Journals > J Cardio-Thoracic Medicine
Depositing User: jctm jctm
Date Deposited: 04 Sep 2017 14:54
Last Modified: 04 Sep 2017 14:54
URI: http://eprints.mums.ac.ir/id/eprint/223

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