Extranodal NK/T Cell Lymphoma with Destruction of the Uvulae: A Case Report

Jabbari Azad, Farahzad and Delavarian, Zahra and Hatami, Masoud and Rahimi, Hosein and Abdolvahedi, Mohammad Reza (2017) Extranodal NK/T Cell Lymphoma with Destruction of the Uvulae: A Case Report. Iranian Journal of Otorhinolaryngology, 29 (2). pp. 101-108.

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Introduction: Extranodal Natural Killer (NK)/T-cell lymphoma (NKTCL) nasal type is a rare but well-known disease with poor prognosis. NKTCL is more prevalent in Asia and comprises about 7-10 of all non-Hodgkin lymphoma cases in this region. The characteristic clinical pattern of NKTCL is the destruction of the midline structures of the mid-face. Case Report: The present study examines a case of NKTCL in a 23-year-old man with a destructive ulcer of the palate and uvulae. Based on immunohistochemical results, after three months of delay, the definitive diagnosis was revealed to be Extranodal NK/T cell lymphoma. Following the third cycle of chemotherapy, the patient died due to sepsis and infection. Conclusion: It is very common to misdiagnose NKTCL with other clinical conditions such as necrotizing stomatitis, deep fungal ulcers, Wegener's Granulomatosis disease, etc. Delay in diagnosis can worsen the course of the disease and its prognosis.

Item Type: Article
Subjects: WV Otolaryngology
Divisions: Journals > Iranian J Otorhinolaryngology
Depositing User: ijo ijo
Date Deposited: 21 Sep 2017 16:30
Last Modified: 21 Sep 2017 16:30
URI: http://eprints.mums.ac.ir/id/eprint/2369

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