Toxicology effects of saffron and its constituents: a review

Badie Bostan, Hasan and Mehri, Soghra and Hosseinzadeh, Hossein (2017) Toxicology effects of saffron and its constituents: a review. Iranian Journal of Basic Medical Sciences, 20 (2). pp. 110-121.

IJBMS_Volume 20_Issue 2_Pages 110-121.pdf

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Saffron (Crocus sativus L.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. The pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. Additionally, other lines of studies have found toxicological effects of saffron. However, a comprehensive review that covers all aspects of its toxicity has not been published yet. The current study provides classified information about the toxic effects of saffron and its constituents in various exposure conditions including acute, sub-acute, sub-chronic and chronic studies. Therapeutic doses of saffron exhibits no significant toxicity in both clinical and experimental investigations.

Item Type: Article
Subjects: QV pharmacology
Divisions: Journals > Iranian J Basic Medical Sciences
Depositing User: ijbms ijbms
Date Deposited: 24 Sep 2017 15:34
Last Modified: 24 Sep 2017 15:34

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