Evaluation of Exfoliative Cytology of Buccal Epithelium in Diabetic Patients

Abdolsamadi, HamidReza and ShahTaheri, Mohsen and Mortazavi, Hamed and Abdollahzadeh, Shermin and Zare, Reza and Vahedi, Mohammad (2009) Evaluation of Exfoliative Cytology of Buccal Epithelium in Diabetic Patients. Journal of Mashhad Dental School, 33 (1). pp. 47-52.

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Introduction: Diabetes mellitus is a complex disease that results in severe metabolic disorders. Recently; great advances about diagnostic criteria of diabetes have occurred. The aim of the present study was cytomorphometric and microscopic analysis of buccal epithelium in diabetic patients in order to find a new procedure for diagnosis. Materials &amp; Methods: In this cohort study, buccal epithelial smear of 12 patients with type I diabetes, 12 patients with type II diabetes, and 24 normal subjects as a control were taken. Papaniculao technique was used for staining the samples and the nuclear and Cytoplasmic area were measured by counting point method. Cytoplasmic / nuclear ratio was calculated. t-test was used for statistical analysis through SPSS13. Results: The epithelial cells of diabetic patients showed binucleation and karyorrhexis. The nuclear and cytoplasmic area as well as cytoplasmic/ nuclear ratio were significantly lower in diabetic patients compared to healthy controls (P<0.05). Conclusion: Diabetes mellitus can produce some alterations in oral epithelial cells. Although these changes are not specific in diabetes, they can be used in diagnosis of this disease.

Item Type: Article
Subjects: WU Dentistry. Oral surgery
Divisions: Journals > Journal of Mashhad Dental School
Depositing User: jmds jmds
Date Deposited: 23 Sep 2017 17:41
Last Modified: 23 Sep 2017 17:41
URI: http://eprints.mums.ac.ir/id/eprint/2994

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