The Prevalence of Celiac Disease in Children with Unexplained Failure to Thrive in South West of Iran

Taheri, Mehri and Sabzali, Sara and Hakim, Ashrafalsadat and Sajadi, Nooshin and Hakimzade, Mehran and Ziaieikajbaf, Tahereh and Cheraghian, Bahman (2017) The Prevalence of Celiac Disease in Children with Unexplained Failure to Thrive in South West of Iran. International Journal of Pediatrics, 5 (4). pp. 4663-4669.

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Abstract

Background Celiac disease (CD), considered as a common chronic and genetic diseases that caused by hypersensitivity to gluten. Failure to thrive (FTT), is one of three major clinical features of CD during childhood. The current study aimed to determine the prevalence of celiac disease in children with unexplained FTT in South West of Iran. Materials and Methods This cross‑sectional study was conducted on 433 children 9-month to 6 years old that diagnosed as unexplained FTT referred to Abuzar Children's Hospital, Ahvaz, South West of Iran, in 2014. In this study, we examined the serum levels of anti-transglutaminase antibody (anti-tTG) in children with unexplained FTT. Data were analyzed using SPSS version 16.0 software. Results The results showed that the prevalence of CD in children with unexplained FTT in was 8.8. The mean scores of children's anti-tTG serum levels in both gender and age groups, showed no significant difference (P> 0.05). Conclusion At current study, the prevalence of CD in children with FTT was 8.8. Since the CD is an important cause of unexplained FTT in children, the early screening and diagnosis and dietary management can be decrease the risk for long-term complications in these children.

Item Type: Article
Subjects: WA Public Health
WS Pediatrics
Divisions: Journals > International J Pediatrics
Depositing User: IJP IJP
Date Deposited: 23 Sep 2017 23:31
Last Modified: 23 Sep 2017 23:31
URI: http://eprints.mums.ac.ir/id/eprint/3147

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