Inflammatory Myofibroblastic Tumor of the Larynx: A Case Report

Izadi, Farzad and Ghanbari, Hadi and Azizi, Mohammad and Gasembaglou, Shahram and Manteghi, Mohammad Javad and Ghanbari, Azadeh (2016) Inflammatory Myofibroblastic Tumor of the Larynx: A Case Report. Iranian Journal of Otorhinolaryngology, 28 (1). pp. 79-82.

IJORL_Volume 28_Issue 1_Pages 79-82.pdf

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Introduction: Inflammatory myofibroblastic pseudotumors are initially described in the lung and various extrapulmonary sites such as the orbits, palatine tonsils, ears, gingiva, pterygomaxillary space, and periodontal tissues. These tumors rarely involve the larynx and predilection to the glottis occurs in an indolent manner. Case Report This case describes a laryngeal myofibroblastic tumor in a 46-year-old woman who presented with an aggressive tumor that extended to the floor of the mouth and the base of the tongue. Extended supraglottic laryngectomy was undertaken for the patient. The diagnosis was spindle cell proliferation with dense lymphoplasma cell infiltration compatible with inflammatory myofibroblastic tumor (Inflammatory pseudotumor or plasma cell granuloma). Definitive diagnosis was achieved with immunohistochemical (IHC) staining. Conclusion: We believe that further IHC studies are required to define the true nature of these tumors especially for those that behave in an aggressive pattern.

Item Type: Article
Subjects: WV Otolaryngology
Divisions: Journals > Iranian J Otorhinolaryngology
Depositing User: ijo ijo
Date Deposited: 26 Sep 2017 16:57
Last Modified: 26 Sep 2017 16:57

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