Utility of the Atopy Patch Test in the Diagnosis of Allergic Rhinitis

Fuiano, Nicola and Incorvaia, Cristoforo (2016) Utility of the Atopy Patch Test in the Diagnosis of Allergic Rhinitis. Iranian Journal of Otorhinolaryngology, 28 (3). pp. 169-175.

IJORL_Volume 28_Issue 3_Pages 169-175.pdf

Download (348kB) | Preview
Official URL: http://ijorl.mums.ac.ir/article_6829.html


Introduction: The diagnostic work-up of allergic rhinitis (AR) is first and foremost based on the combination of clinical history data and results of skin prick tests (SPT). Other tests, including specific IgE measurement, nasal challenge, and, as a third option, component resolved diagnosis or basophil activation test, may be useful when the diagnosis is difficult because of polysensitization or when negative results of SPT are observed despite a suggestive history for allergy. The atopy patch test (APT) that assesses the type 4 delayed hypersensitivity allergy is currently not sufficiently used. The data obtained in recent studies on the diagnostic utility of the APT in patients with AR was reviewed. Data Sources: Review of the literature. Conclusion: The data from available studies show that the APT is frequently positive in patients with AR, especially when there is a positive history for atopic dermatitis. Very often, APT is the only positive test and therefore performing only SPT or in vitro IgE measurement may lead to an erroneous diagnosis of nonallergic rhinitis. Recent data suggest a role for APT not only for diagnosis but also in epidemiological investigation on respiratory allergy.

Item Type: Article
Subjects: WV Otolaryngology
Divisions: Journals > Iranian J Otorhinolaryngology
Depositing User: ijo ijo
Date Deposited: 25 Sep 2017 14:02
Last Modified: 25 Sep 2017 14:02
URI: http://eprints.mums.ac.ir/id/eprint/3350

Actions (login required)

View Item View Item