Correlation of helicobacter pylori infection seropositivity and hyperemesis gravidarum

Hassanzade Mofrad, Maliheh and Ayati, Sedigheh and Ayatollahi, Hosein and Sima, Hamidreza and Shakeri, Mohammad Tghi and Hasanalizadeh Haghighi, Shadi and Malakouti, Hasan (2015) Correlation of helicobacter pylori infection seropositivity and hyperemesis gravidarum. The Iranian Journal of Obstetrics, Gynecology and Infertility, 18 (142). pp. 1-5.

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Introduction: Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting during pregnancy which occurs in 0.5 to 2 of pregnancies. Its etiology is unknown, hormonal and psychological factors are attributable to the condition. In the recent studies, helicobacter pylori infection has been proposed as possible factor. This study was performed with the aim to evaluate the relationship between helicobacter pylori infection and nausea and vomiting during pregnancy. Methods: This prospective and case-control study was performed on 87 pregnant women referred to Ghaem and Imam Reza hospitals, Mashhad University of Medical Sciences from 2007-2008. Forty three pregnant women with hyperemesis gravidarum and forty four pregnant women without symptom were evaluated in terms of helicobacter pylori infection with serology of IgG antibody against Helicobacter pylori. Analysis of data was performed using SPSS statistical software (version 16) and chi-square and t-student tests. PResults: In this study, 36 women of cases group (81.8) and 25 women of control group (58.1) had high serology of IgG antibody against Helicobacter pylori and this difference was statistically significant (P=0.016) Conclusion: there is a significant relation between hyperemesis gravidarum and positive IgG antibody against Helicobacter pylori.

Item Type: Article
Subjects: WP Gynecology
WQ Obstetrics
Divisions: Journals > Iranian J Obstetrics, Gynecology and Infertility
Depositing User: ijogi ijogi
Date Deposited: 24 Sep 2017 15:02
Last Modified: 24 Sep 2017 15:02

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