Analgesia Following Arthroscopy � a Comparison of Intraarticular Bupivacaine and/or Midazolam and or Fentanyl

Nahravani, Mahmoud and Moosavi Tekye, Seyed Mostafa and Alipour, Mohammad and Makhmalbaf, Hadi and Afzal Aghaee, Monnavar (2017) Analgesia Following Arthroscopy � a Comparison of Intraarticular Bupivacaine and/or Midazolam and or Fentanyl. The Archives of Bone and Joint Surgery, 5 (1). pp. 28-31.

ABJS_Volume 5_Issue 1_Pages 28-31.pdf

Download (742kB) | Preview
Official URL:


 Background: Arthroscopic intervention is very common for conducting orthopedic surgeries. After a knee arthroscopic surgery, different drugs are used through intra-articular administration to induce analgesia. The aim of this study was to evaluate analgesic effects of Bupivacaine (marcaine), Bupivacaine plus midazolam, and Bupivacaine plus fentanyl in reducing pain after knee arthroscopic surgery. Methods: Frothy five patients who were candidate for knee arthroscopy were divided into three groups. Group A, B and C received Bupivacaine (50 mg), Bupivacaine (50 mg) plus midazolam (50 μg/kg), and Bupivacaine (50 mg) plus fentanyl (3 μg/kg), respectively. The analgesic solutions were diluted with normal saline up to 20 ml. The analgesic effects were evaluated by VAS during first 24 hrs after surgery. With the VAS > 4, extra analgesic (pethidine) was administrated for patient. Results:The amount of induced analgesia and need for extra analgesic was different between groups; however, it was not statistically significant (p<0.109). The amount of administered analgesic (pethidine) in first 24 hours post-operatively was 275 mg for group A, while it was 150 mg for group B and 75 mg for group C. In group A, 46.67 of patients required further analgesic while this was 26.67 and 13.34 for groups B and C respectively (p<0.109). Conclusion: Intra-articular administration of studied drugs in all three groups reduced post-operation pain. The amount of induced analgesia was the highest for group C, while group B drugs induced better analgesia compared to group C.

Item Type: Article
Subjects: WE Musculoskeletal system
WO Surgery
Divisions: Journals > Archives of Bone & Joint Surgery
Depositing User: abjs abjs
Date Deposited: 24 Sep 2017 17:03
Last Modified: 24 Sep 2017 17:03

Actions (login required)

View Item View Item