Drug resistance pattern of carbapenem-resistant Acinetobacter baumannii isolated from a referral burn center in northeast of Iran

Sarhaddi, Nazanin and Dolatabadi, Samaneh and Amel Jamehdar, Saeid (2016) Drug resistance pattern of carbapenem-resistant Acinetobacter baumannii isolated from a referral burn center in northeast of Iran. medical journal of mashhad university of medical sciences, 59 (1). pp. 1-8.

[img]
Preview
Text
MJMS_Volume 59_Issue 1_Pages 1-8.pdf

Download (896kB) | Preview
Official URL: http://mjms.mums.ac.ir/article_6981.html

Abstract

Introduction: Acinetobacter baumannii, an opportunistic gram negative bacteria, is a threat in hospital infections, especially in ICU wards due to the high survival ability and talent to get different antibiotic resistance. So far, there are few reports about sensitivity patterns of multi-drug resistant Acinetobacter baumannii (MDR), especially carbapenem resistance from various hospitals in Mashhad, Iran. Methods: In this study 54 strains of MDR from referral burn unit of Imam Reza hospital in Mashhad were collected during October to March 2013. Sensitivity pattern to antibiotics was determined by Kirby-Bauer method for each isolate. Frequency of various genes responsible for resistance to carbapenem was studied for each isolte by PCR method. Results: The rate of resistance to tested antibiotics was more than 95. In addition, this study showed the high prevalence of blaVIM, blaIMP, blaTEM, blaADC, OXA-Like23, OXA-Like24, OXA-Like51, OXA-Like58 and ISAba1 genes, that mediated resistance to betalactam antibiotics. Conclusion:These results indicate that all isolates were resistant to betalactam antibiotics. These results suggest more study on rational usage of carbapenems for treatment of infections by Acinetobacter baumannii.

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 25 Sep 2017 14:25
Last Modified: 25 Sep 2017 14:25
URI: http://eprints.mums.ac.ir/id/eprint/3890

Actions (login required)

View Item View Item