Evaluation of the Effect of Oral Saffron Capsules on Pain Intensity during the Active Phase of Labor

Azhari, Sedighe and Ahmadi, Sedighe and Rakhshandeh, Hasan and Jafarzadeh, Hooriye and Mazlom, Seyed Reza (2014) Evaluation of the Effect of Oral Saffron Capsules on Pain Intensity during the Active Phase of Labor. The Iranian Journal of Obstetrics, Gynecology and Infertility, 17 (115). pp. 1-10.

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Abstract

Background: For many women, childbirth is considered the most painful experience of their lives. Fear of natural delivery is the main cause of women’s inclination towards cesarean section. Effects of saffron and its active ingredients have been shown to alleviate a variety of neurological and inflammatory pains; however, the effect of saffron on labor pain has not been yet investigated. This study was performed to determine the effect of oral saffron capsules on pain during the active phase of labor. Methods: This triple-blind clinical trial was conducted on 60 eligible women, who were candidates for normal vaginal delivery at 17 Shahrivar Hospital of Mashhad, Iran in 2013-2014. The subjects were randomly divided into intervention (using saffron capsules, 250 mg) and control (receiving placebo capsules) groups. At the beginning of the active phase of labor, one capsule (the saffron or placebo capsule) was used by the subject. Pain intensity was measured at the beginning of the study and then every hour until the end of the active phase of labor, using a visual analog scale. For data analysis, Chi-square, t-test, Mann-Whitney, and variance analysis were performed, using SPSS version 11.5. P-value less than 0.05 was considered statistically significant. Results: The mean overall pain intensity was 85.9±8.4 in the intervention group and 97.4±2.9 in the control group; the difference was statistically significant (P<0.001). Before the intervention, the mean anxiety score in the intervention group was not significantly different from that observed in the placebo group (P=0.824). Maternal/neonatal complications were observed in none of the subjects of the two groups. Conclusion: Considering an 11.8 reduction in the pain intensity of nulliparous women using saffron capsules and the absence of any associated complications, these capsules can be used as a mild analgesic for labor pain

Item Type: Article
Subjects: WP Gynecology
WQ Obstetrics
Divisions: Journals > Iranian J Obstetrics, Gynecology and Infertility
Depositing User: ijogi ijogi
Date Deposited: 25 Sep 2017 16:36
Last Modified: 25 Sep 2017 16:36
URI: http://eprints.mums.ac.ir/id/eprint/4201

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