Evaluation of Sonography and Thyroid Function Tests in Patients with Polycystic Ovary Syndrome

Layegh, Parvin and Farokh, Donya and Baghaei, Mahdieh and Salehi, Maryam and Layegh, Parvaneh (2014) Evaluation of Sonography and Thyroid Function Tests in Patients with Polycystic Ovary Syndrome. The Iranian Journal of Obstetrics, Gynecology and Infertility, 17 (93). pp. 5-19.

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Introduction: Polycystic ovary syndrome (PCOS) is associated with insulin resistance and hyperinsulinemia. Insulin as a growth factor induces cellular proliferation in all tissues such as thyroid. We studied functional tests and sonographic findings of thyroid in patients with PCOS and assessment the relationship between the level of thyroid-stimulating hormone (TSH) and insulin resistance. Methods: This cross sectional study was conducted on 98 patients with PCOS in the age range of 16 to 42 years in Mashhad, Iran in 2012-2013. Height, weight, thyroid function tests, fasting blood sugar (FBS), fasting insulin and thyroid sonography was measured for all patients. Data were analyzed using SPSS software version 11.5 and t-test, Mann-Whitney, chi-square and Fisher tests. P value less than 0.05 was considered significant. Results: 10 patients (10.2) had high level of TSH, 12 patients (12.24) had high anti-TPO and 8 cases (8.16) had high anti-TPO with thyroid heterogenicity in sonography. 5 patients (5.10) had high anti-TPO and high TSH and 8 cases (8.16) had high TSH and thyroid heterogenicity in sonography. 31 patients (31.6) had decreased echogenicity and 25 patients (25.5) had thyroid heterogenicity and 20 cases (20.4) had thyroid nodule in sonography. There were no statistically significant differences between the level of TSH, anti-TPO, T3, free T4 and sonographic findings in PCOS patients with and without insulin resistance (p>0.05). Conclusion: Compare to general population, it is not recommended routine sonography in PCOS patients but it is recommend to measure of TSH for detection of thyroid dysfunction in these patients.

Item Type: Article
Subjects: WP Gynecology
WQ Obstetrics
Divisions: Journals > Iranian J Obstetrics, Gynecology and Infertility
Depositing User: ijogi ijogi
Date Deposited: 25 Sep 2017 17:07
Last Modified: 25 Sep 2017 17:07
URI: http://eprints.mums.ac.ir/id/eprint/4275

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