The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients

Arabi, Seyed Mostafa and Hejri Zarifi, Sudiyeh and Nematy, Mohsen and Safarian, Mohammad (2015) The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients. Journal of Fasting and Health, 3 (2). pp. 74-80.

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Purpose: The aim of this study was to compare biochemical tests, body composition and anthropometric parameters in Nonalcoholic Fatty Liver Disease (NAFLD) patients before and after Ramadan fasting. Methods: fifty NAFLD patients including 33 males and 17 females aged 18-65 year, were recruited. Subjects attended after diagnosis based on ultrasound imaging, with at least 10 hour fasting, before and after Ramadan who were been fasting for at least 10 days. A fasting blood sample was obtained, blood pressure was measured and body mass index(BMI) and fat mass (FM) and fat free mass (FFM) were calculated. Lipid profile, fasting blood sugar (FBS),insulin, ALT and AST enzymes were analyzed on all blood samples. Result: There was a significant increase in HDL-c in females and higher total plasma cholesterol, triglyceride (TG) and FBS in both gender while lower systolic blood pressure (SBP), diastolic blood pressure (DBP) and ALT decreasing after Ramadan (P<0.05, t test), the change in BMI, LDL- c, FM and FFM after Ramadan were not significant (P>0.05, t test). Conclusion: This study shows significant effects on NAFLD patient parameters during Ramadan fasting such as decreasing in insulin, ALT enzyme, SBP and DBP and increasing in HDL-c after an average of 27 d fasting, Result from this study suggested that Ramadan fasting may be useful to improve NAFLD, so further studies are needed in this area.

Item Type: Article
Subjects: WD Nutrition Disease and metabolic diseases
QT physiology
Divisions: Journals > J Fasting And Health
Depositing User: fasting fasting
Date Deposited: 25 Sep 2017 17:42
Last Modified: 25 Sep 2017 17:42

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