HIV-1/HTLV Co-Infection: a Survey of Molecular Basis with Clinical Studies

Saberi, Marzieh and Tavanaii sani, Ashraf (2017) HIV-1/HTLV Co-Infection: a Survey of Molecular Basis with Clinical Studies. Journal of Patient Safety & Quality Improvement, 5 (1). pp. 497-501.

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Human immunodeficiency virus type-1 (HIV�1) and human T-cell leukemia virus (HIV-1/HTLV) co-infection is a serious health problem worldwide, especially in endemic areas and vulnerable subjects like intravenous drug abusers. This is due to the fact that CD4+ and CD8+ T-cells are the primary targets of HTLV-1 and HTLV-2, respectively. The influence of HTLV-1 and HTLV-2 on CD4+ count can shortened or prolong progression to AIDS and the development of more clinical complications. Opportunistic infections may differ between HIV-1/HTLV-1 and HIV-1/HTLV-2 co-infection subjects. Several epidemiologic studies have discussed molecular bases of HIV-1/HTLV co-infection, including cytokine and chemokine mediated pathways; however, they have yielded discrepant results.

Item Type: Article
Subjects: QY Clinical Pathology
Divisions: Journals > J Patient Safety & Quality improvement
Depositing User: psj psj
Date Deposited: 04 Sep 2017 14:24
Last Modified: 04 Sep 2017 14:24

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