Fabrication and Optimization of a PAGATA Gel Dosimeter: Increasing the Melting Point of the PAGAT Gel Dosimeter with Agarose Additive

Azadbakht, Bakhtiar and Zahmatkesh, Mohammad Hassan and Haddad, Kamal and Bagheri, Saeid (2010) Fabrication and Optimization of a PAGATA Gel Dosimeter: Increasing the Melting Point of the PAGAT Gel Dosimeter with Agarose Additive. Iranian Journal of Medical Physics, 7 (4). pp. 1-6.

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Abstract

Introduction: The PAGAT polymer gel dosimeter melts at 30 �C and even at room temperature during the summer, so it needs to be kept in a cool place such as a refrigerator. To increase the stability of the PAGAT gel, different amounts of agarose were added to the PAGAT gel composition and the PAGATA gel was manufactured. Material and Methods: The PAGATA gel vials were irradiated using a Co-60 machine. Then, the samples were evaluated using a 1.5 T Siemens MRI scanner. The ingredients of the PAGATA normoxic gel dosimeter were 4.5 N-N' methylen-bis-acrylamide, 4.5 acrylamide, 4.5 gelatine, 5 mM tetrakis (THPC), 0.01 mM hydroquinone (HQ), 0.5 agarose and 86 de-ionized water (HPLC). Results: Melting point and sensitivity of the PAGAT gel dosimeter with addition of 0.0, 0.3, 0.5, 1.0, 1.5 and 2.0 of agarose were measured, in which the melting points were increased to 30, 82, 86, 88, 89 and 90°C and their sensitivities found to be 0.113, 0.1059, 0.125, 0.122, 0.115 and 0.2  respectively. Discussion and Conclusions: Adding agarose increased the sensitivity and background R2 of the evaluated samples. The optimum amount of agarose was found to be 0.5 regarding these parameters and also the melting point of the gel dosimeter. A value of 0.5 agarose was found to be an optimum value considering the increase of sensitivity to 0.125 and melting point to 86°C but at the expense of increasing the background R2 to 4.530.

Item Type: Article
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Journals > Iranian J Medical Physics
Depositing User: ijmp ijmp
Date Deposited: 27 Sep 2017 14:15
Last Modified: 27 Sep 2017 14:15
URI: http://eprints.mums.ac.ir/id/eprint/5206

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