Study of Different Tissue Density Effects on the Dose Distribution of a 103Pd Brachytherapy Source Model MED3633

Mowlavi, Ali Asghar and Yazdani, Majed (2010) Study of Different Tissue Density Effects on the Dose Distribution of a 103Pd Brachytherapy Source Model MED3633. Iranian Journal of Medical Physics, 7 (3). pp. 55-62.

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Abstract

Introduction: Clinical application of encapsulated radioactive brachytherapy sources has a major role in cancer treatment. In the present research, the effects of different tissue densities on the dose distribution of a 103Pd brachytherapy source in a spherical phantom of 50 cm radius have been studied. Material and Methods: As is well known, absorbed dose in tissue depends to its density, but this difference is not clear in measurements. Therefore, we applied the MCNP code to evaluate the effect of density on the dose distribution. 103Pd brachytherapy sources are used to treat prostate, breast and other cancers. Results: Absorbed dose has been calculated and presented around a source placed in the center of the phantom for different tissue densities. Also, we derived anisotropy and radial dose functions and compared our Monte Carlo results with experimental results of Rivard and Li et al. for F(1, θ) and g(r) in 1.040 g/cm3 tissue. Conclusion: The results of this study show that relative dose variations around the source center are very considerable at different densities, because of the presence of a photoabsorber (Au-Cu alloy) in the source core. Dose variation exceeds 80 at the point (Z = 2.4 mm, Y = 0 mm). Computed values of anisotropy and radial dose functions are in good agreement with the experimental results of Rivard and Li et al.  Â

Item Type: Article
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Journals > Iranian J Medical Physics
Depositing User: ijmp ijmp
Date Deposited: 27 Sep 2017 14:21
Last Modified: 27 Sep 2017 14:21
URI: http://eprints.mums.ac.ir/id/eprint/5231

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