Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis

Bezheh, Nahid and Soltani, Mahmod and Khaleghzade, Homa (2014) Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis. Evidence Based Care, 4 (2). pp. 63-72.

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Abstract

Background: Multiple Sclerosis is the most prevalent disease of the central nerve system. This disease affects different aspects of patient�s life. Multiple Sclerosis has negative effects on physical and mental health. Cytokines play an important role in the pathogenesis of Multiple Sclerosis and are major targets of therapeutic interventions. Aim: To investigate the effects of aquatic aerobic exercise on IL-6 and IL-10 in men with Multiple Sclerosis. Methods: In this randomized clinical trial, 30 patients with MS were randomly divided into two control and experimental groups. For experimental group, exercise program was applied for 8 weeks, 3 sessions per week with intensity of 50-60 of maximum heartbeat. IL-6 and IL-10 were analyzed before and after exercises. Analyzing data was done by SPSS ver. 18, and 0.05 significant level of independent T examination. Results: Results indicated that there was significant difference between the two groups in IL-6 (P<0/001) and IL-10 (P<0/004). Conclusion: aerobic training in watercan regulate the inflammatory and anti-inflammatory cytokines, and adjust IL-6 and IL-10 indexes. Experts can use these exercises as complementary treatment along with medical cure for MS patients.

Item Type: Article
Subjects: WY Nursing
Divisions: Journals > Evidence-based Care
Depositing User: ebcj ebcj
Date Deposited: 19 Sep 2017 12:32
Last Modified: 19 Sep 2017 12:32
URI: http://eprints.mums.ac.ir/id/eprint/532

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