Review of Natural History, Benefits and Risk Factors Pediatric Liver Transplantation

Karjoo, Manoochehr and Banikazemi, Maryam and Saeidi, Masumeh and Kiani, Mohammad Ali (2016) Review of Natural History, Benefits and Risk Factors Pediatric Liver Transplantation. International Journal of Pediatrics, 4 (3). pp. 1529-1544.

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Abstract

Liver or hepatic transplantation (LT) is the replacement of a diseased liver with part or whole healthy liver from another person (allograft). Human liver transplants were first performed by Thomas Starzl in the United States and Roy Calne in Cambridge, England in 1963 and 1967, respectively. Liver transplantation is a viable treatment option for end-stage liver disease and acute liver failure. Pediatric patients account for about 12.5 of liver transplant recipients. The most commonly used technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic location as the original liver. Cirrhosis, or liver injury, is a common reason why adults need liver transplants and children with bile duct disease issues are often the candidates. Survival statistics depend greatly on the age of donor, age of recipient, skill of the transplant center, compliance of the recipient, whether the organ came from a living or cadaveric donor and overall health of the recipient. Survival rates improve almost yearly, due to improved techniques and medications.

Item Type: Article
Subjects: WA Public Health
WS Pediatrics
Divisions: Journals > International J Pediatrics
Depositing User: IJP IJP
Date Deposited: 28 Sep 2017 00:20
Last Modified: 28 Sep 2017 00:21
URI: http://eprints.mums.ac.ir/id/eprint/5515

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