Evaluation of Transvaginal Ultrasonography in Premalignant and Malignant Changes in Postmenopausal Bleeding

Nazari, T and Arabi, L (2006) Evaluation of Transvaginal Ultrasonography in Premalignant and Malignant Changes in Postmenopausal Bleeding. The Iranian Journal of Obstetrics, Gynecology and Infertility, 9 (1). pp. 75-80.

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Background: Postmenopausal bleeding (PMB) is a common problem of elderly women. Golden standard diagnostic method is the pathologic report of Dilatation and Curettage (D&C). In recent studies Transvaginal Ultrasonography (TVS) is discussed as a noninvasive useful method for screening malignancy change in the endometrium. We evaluated vaginal sonography in uterine malignancy. Methods & Materials: This was an analytical “Clinical Trial” study performed in menopause women who referred to specialized Clinics of Gynecology in Babol. Inclusion criteria were PMB and no hormonal treatment. D&C endometrial sampling and TVS were accomplished for all individuals.. Result: The most common pathologic diagnosis in 50 cases, were studied was proliferating endometrium means. Endometrial thickness in them was 12.6±10.4mm. No malignancy was reported in less than 5 mm endometrial thickness. Mean of endometrial thickness in 4 cases (8), which had malignant changes, was 17.6±13.3 mm. malignant changes in these patients were adenocarcinoma and hyperplasia. Sensitivity of TVS was 100 and specificity was 26. Positive predictive value was 10.6 and negative predictive value was 100. Efficacy of this method was 32. Conclusion: TVS isnot a reliable diagnostic test for malignancy or premalignancy screening in PMB, if we get endometrial thickness as the only basis of evaluation. But it is reliable in follow-up of patient with less than 5-mm endometrial thickness. It seems that pathologic assessment is still the golden standard for malignancy diagnosis.

Item Type: Article
Subjects: WP Gynecology
WQ Obstetrics
Divisions: Journals > Iranian J Obstetrics, Gynecology and Infertility
Depositing User: ijogi ijogi
Date Deposited: 28 Sep 2017 14:25
Last Modified: 28 Sep 2017 14:25
URI: http://eprints.mums.ac.ir/id/eprint/6156

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