Effect of Corneal Cross-Linking on the Tear Osmolarity in Progressive Keratoconus Patients

Gheibi, A and Aghazadeh Amiri, M and Askarizadeh, F and Tabatabaie, M and Salamat Rad, A and Khorrami-Nejad, M (2016) Effect of Corneal Cross-Linking on the Tear Osmolarity in Progressive Keratoconus Patients. Journal of Paramedical Sciences & Rehabilitation, 5 (2). pp. 7-13.

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Purpose: This study was conducted to assess the effect of corneal cross-linking on tear film osmolarity in patients with progressive keratoconus using the TearLab device. Methods: 66 eyes of 66 patients including 40 men and 26 women with age range of 15 to 35 years old with progressive keratoconus who were candidates for corneal cross-linking surgery, were evaluated in this prospective study. These indicated patients for corneal cross-linking surgery had no history of eye or systemic disease associated with ocular manifestations. They hadn't worn contact lenses since 3 weeks before study and also they hadn't used drugs (effective on tear layer) or contact lenses for 6 months after surgery except their treatment period. Tear osmolarity was measured preoperatively and 6 months after surgery using the TearLab device. After all, data analysis was performed by descriptive and analytical statistical methods. Results: The mean Osmolarity before the corneal cross-linking surgery is 303.82±15.50 mOsm/L and after the surgery is 306.64±14.49 mOsm/L. There is no significant difference in tear film Osmolarity before and after the corneal cross-linking (P=0.192). Conclusion: Corneal cross-linking had no significant impact on tear film osmolarity in progressive keratoconus patients and we can’t consider dry eye as a side effect of corneal cross-linking.

Item Type: Article
Subjects: WW Ophthalmology
Divisions: Journals > Journal of Paramedical Science and Rehabilitation
Depositing User: jpsr jpsr
Date Deposited: 28 Sep 2017 14:27
Last Modified: 28 Sep 2017 14:27
URI: http://eprints.mums.ac.ir/id/eprint/6168

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