Vitamin D and respiratory disorder

Hushmand, Mahnaz and Behmanesh, Fatemeh and Ahanchian, Hamid and Khalesi, Maryam and Ataei, Alireza (2015) Vitamin D and respiratory disorder. Reviews in Clinical Medicine, 2 (4). pp. 195-199.

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Abstract

The active form of vitamin D is synthesized in some body organs following sun exposure and dietary intake. Vitamin D exhibits its major and critical effects not only through regulation of calcium and phosphate metabolism but also by influencing on respiratory and immune system. Serum concentrations of 25-hydroxyvitamin D below the optimum limit lead to vitamin D insufficiency or maybe deficiency. These inappropriate concentrations of vitamin D lead to different types of pulmonary diseases such as viral and bacterial respiratory infection, asthma, chronic obstructive pulmonary disease, and cancer. In this review we described the association between vitamin D deficiency and severe therapy resistant asthma. We also reviewed the underlying molecular mechanism of vitamin D deficiency in children with severe- therapy resistant asthma. Based on current information, future clinical trial are needed to study the role of vitamin D supplementation on different groups of patients with severe asthma including infants, children of school age, and ethnic minorities.

Item Type: Article
Subjects: WF Respiratory System
Divisions: Journals > Reviews in Clinical Medicine
Depositing User: RCM RCM
Date Deposited: 28 Sep 2017 16:02
Last Modified: 28 Sep 2017 16:02
URI: http://eprints.mums.ac.ir/id/eprint/6349

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