Introduction of Hematological and Molecular Algorithms for Diagnosis of Factor XIII Deficiency in Iran Laboratories

Dorgalaleh, A and Tabibian, Sh and Dadashizadeh, Gh and Kazemi, A and Zaker, F and Alizadeh, Sh and Naderi, M and Hosseini, S and Varmaghani, B and Rashid panah, J (2015) Introduction of Hematological and Molecular Algorithms for Diagnosis of Factor XIII Deficiency in Iran Laboratories. Journal of Paramedical Sciences & Rehabilitation, 4 (3). pp. 7-16.

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Abstract

Purpose: Factor XIII deficiency (FXIIID) is an extremely rare hemorrhagic disorder with an approximately 12 higher incidence in comparison with reported global incidence of the disorder. A standard diagnostic algorithm was proposed by the International Society of Thrombosis and Hemostasis (ISTH) for FXIIID, however, due to the lack of investments all parts of this algorithm cannot be applied in Iran. Thus, this study presented a national algorithm for diagnosis of FXIIID in Iran. Methods: For presentation of a national algorithm, all previously published data about Iranian patients with FXIIID as well as practical methods for diagnosis of FXIIID were collected using Science Direct, Google Scholar and PubMed databases. Results: With available facilities, an algorithm with regards to the laboratory assessment, clinical presentations as well as family history can be suitable for an on time and less expensive diagnosis of FXIIID in Iran. Conclusion: Since ISTH diagnostic algorithm is expensive and time consuming, an economical and more suitable national algorithm with regards to available equipment may reduce the rate of misdiagnosis and its life-threatening consequences.

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Journals > Journal of Paramedical Science and Rehabilitation
Depositing User: jpsr jpsr
Date Deposited: 28 Sep 2017 15:25
Last Modified: 28 Sep 2017 15:25
URI: http://eprints.mums.ac.ir/id/eprint/6368

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