A History of Burkholderia-caused Infections in Iran

Arefnejad, M and Tajzadeh, P and Barjesteh, A (2013) A History of Burkholderia-caused Infections in Iran. Journal of Paramedical Sciences & Rehabilitation, 2 (2). pp. 54-59.

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Purpose: The first report of Burkholderia caused- Infection in Iran dated back to forty years ago which showed this type of infection was limited among animal population. Recently, according to human case reports in Iran, little is reported about this infection and it is not considered in laboratory and clinical domains. Thus, the main aim of this study was to investigate the Burkholderia –caused infections in clinical and diagnostic systems. Methods: This review-article was performed after searching through NCBI, MEDLINE, SCOPUS, ISI, WHO and CDC data banks and it has been updated until submission date to the journal. The old data was collected through the earlier versions of journals, books and inter-& external related seminars. Results: The first Burkholderia-caused infection history in Iran was reported among horses from Razi Institute which inoculated with Burkholderia pseudomallei for vaccine production in 1970. Later on, one human case with pneumonia was reported in 1977. After a big gap, in 2004, the Iranian Burkholderia cepacia complex genomovars was isolated and identified among pneumonia in Cystic Fibrosis patients. At Tehran zoo, Glanders in imported Siberian tigers was reported at 2011 and finally the human isolated Burkholderia pseudomalleus in an individual traveler to endemic area was announced in 2012. Conclusion: According to the recent Burkholderia species isolated from human population in Iran, the uncertain prevalence of Burkholderia-caused infection, mis-identification of Burkholderia genus in clinical samples and the resistance of some Burkholderia to antibiotics, it seems logical that the clinical and para-clinical researches should pay more attention on this bacteria through diagnostic and clinical approaches and determine the real state of this type of infection.

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Journals > Journal of Paramedical Science and Rehabilitation
Depositing User: jpsr jpsr
Date Deposited: 28 Sep 2017 16:35
Last Modified: 28 Sep 2017 16:35
URI: http://eprints.mums.ac.ir/id/eprint/6485

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