Effect of Phototherapy on Serum Magnesium Level in Term Neonates with Hyperbilirubinemia

Ahmadpour-kacho, Mousa and Zahedpasha, Yadollah and Soleimani Rad, Hossein (2014) Effect of Phototherapy on Serum Magnesium Level in Term Neonates with Hyperbilirubinemia. medical journal of mashhad university of medical sciences, 57 (6). pp. 751-755.

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Abstract

Introduction Several adverse effects including hypocalcemia have been reported for phototherapy in the treatment of neonatal hyperbilirubinemia, but less have been reported regarding the effect of phototherapy on serum magnesium level. This study was carried out to determine the effect of phototherapy on serum Mg level in term neonate with hyperbilirubinemia. Materials and Methods In a cohort study in 2012 all term neonates admitted for the treatment of hyperbilirubinemia, according to the local protocol, included. All sick babies and those who required exchange transfusion excluded. A blood sample for magnesium level assessment was taken before and also after 72 hr of conventional phototherapy. The serum magnesium levels before and after phototherapy were compared and a P- value less than 0.05 was considered being significant. Results Overall one hundred and twenty neonates studied. The mean gestational age was 39.01± 0.974 weeks and the mean birth weight was 3359.17 ± 426 grams. The mean serum magnesium level before the phototherapy was 2.869 ± 0.367 mg/dl and 72 hrs after the phototherapy decreased to 2.604±0.292 mg/dl (p value =0.001). No sign and symptom attributable to hypomagnesemia were observed. Conclusion Phototherapy could decrease the serum magnesium level in term neonate with hyperbilirubinemia and the amount of this decrease could not cause any sign and symptom.   Acknowledgement: The authors wish to thank the Clinical Research Development Committee of Amirkola Children's Hospital, Mrs. Faeze Aghajanpour, Dr Pornasrollah M. and Mrs Mazloomi A. for their contribution to this study. This study was supported by a research grant as a thesis of Neonatal Fellow Training Course for Dr Soleimani Rad H. from the Non-Communicable Pediatric Diseases Research Center of Babol University of Medical Sciences (Grant Number: 9134856).

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 02 Oct 2017 14:42
Last Modified: 02 Oct 2017 14:42
URI: http://eprints.mums.ac.ir/id/eprint/7040

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