Clinical significance of DVM and its prevalence in pre-gestational diabetes cases versus normal pregnancies

Akhlaghi, Farideh and Akhondzadeh, Mahnaz (2015) Clinical significance of DVM and its prevalence in pre-gestational diabetes cases versus normal pregnancies. Reviews in Clinical Medicine, 2 (3). pp. 135-137.

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Abstract

Pre-gestational diabetes mellitus affects less than 1 of all pregnancies and is a significant cause of fetal morbidity and mortality. It is hypothesized that impaired placental function, in the form of abnormal placental weight and/or abnormal placental histology, may be responsible for this event in such pregnancies. Delayed villous maturation of placental villi, which is one of the findings associated with pre-gestational diabetes increases the rate of perinatal mortality. There is limited literature regarding the delayed maturation of placental villous. This review included trials (randomized and non-randomized), cohort and case-control studies registered in Medline/PubMed database, from January 2001 to September 2012 that evaluated the clinical significance of delayed villous maturation and its prevalence in pre-gestational diabetic cases compared to normal pregnancies.It emphasizes that further studies with focus on possible clinical or ultrasound markers of placental delayed villous maturation, especially in a high risk-group such as women with pre-gestational diabetes mellitus are highly recommended.

Item Type: Article
Subjects: WP Gynecology
WQ Obstetrics
Divisions: Journals > Reviews in Clinical Medicine
Depositing User: RCM RCM
Date Deposited: 02 Oct 2017 17:23
Last Modified: 02 Oct 2017 17:23
URI: http://eprints.mums.ac.ir/id/eprint/7128

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