The Prevalence of Celiac Sprue in Adult Patients with Type I Diabetes

Vosughinia, Hassan and Nezam, Seyed Kazem and bayani, Mahtab and Saadatnia, Hasan and Aboutorabi, Robabeh Beygom and Bakhshipour, Alireza and Kaykhaei, Mahmoud Ali and Mashhadi, Mohammad Ali (2012) The Prevalence of Celiac Sprue in Adult Patients with Type I Diabetes. medical journal of mashhad university of medical sciences, 55 (3). pp. 178-182.

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Introduction  The prevalence of celiac sprue increases in patients with IDDM. This relation between type I diabetes mellitus and celiac sprue is important with respect to too presence of diarrhea in both diseases. When a patient with type I diabetes mellitus complains from diarrhea, physician should be alert about the presence of celiac sprue and may need to do some workup to rule out celiac sprue. Materials and Methods: This is a cross sectional and discretional study. There were 87 type I diabetes mellitus patients referred to endocrine clinic of Mashhad Qaem hospital between1384-1387. According to inclusion criteria each patient referred to selected laboratory for checking tTG-IgA Antibody, and if it was positive she or he referred to endoscopy ward of Qaem hospital for doing endoscopy and taking biopsy from distal part of the  second potion of duodenum.     Results In this study, 87 patients with type I diabetes mellitus having the mean age of 19.78 years (lower limit of 15 and upper limit of 30) were under study (41 males and 46 females). Positive anti tTG-IgA antibody reported for 28 patients (32.2). There were 9 individuals with biopsy proven celiac sprue in these 87 patients (10.3). Also 24 persons (27.6) suffered from diarrhea and or abdominal pain among 87 patients. Conclusion Prevalence of celiac sprue is different in different geographical areas. This prevalence in type I diabetic patients in east of Iran was about 10.3. This study shows the necessity of screening among patients with type I diabetes mellitus. Â

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 02 Oct 2017 16:30
Last Modified: 02 Oct 2017 16:30

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