Diagnostic Accuracy of Polyclonal Stool Antigen for Detection of Helicobacter Pylori Infection in Children

Jafari, Seyyed Ali and Kianifar, Hamidreza and Khakshoor, Ali and Hiradfar, Simin and Zabolinejad, Nona and Khodashenas, Ezzat (2010) Diagnostic Accuracy of Polyclonal Stool Antigen for Detection of Helicobacter Pylori Infection in Children. medical journal of mashhad university of medical sciences, 53 (3). pp. 158-162.

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Abstract

Introduction  Helicobacter pylori infection has various clinical features. One of the most common presentations of this infection is upper abdominal pain. Complications such as gastritis, gastric ulcer, gastric carcinoma and MALT lymphoma mandate early diagnosis of H.P infection by a low cost and non invasive manner. The aim of this study was to evaluate the diagnostic role of H.P stool antigen detection as a simple and non invasive method for diagnosis of this infection.  Materials and Methods  Upper endoscopy with gastric biopsy was done on all patients between 6 months to 18 years old with upper abdominal pain. Stool test was done by polyclonal anti-h.p antibody. Results of stool Test were compared with results of RUT and histologic examination  Results  Overall 110 patients (57 boys,53 girls) were studied, 32 patients were Helicobacter pylori positive and 78 patients were Helicobacter pylori negative based on RUT and histologic examination. Stool antigen testing was positive for 39 patients. Sensitivity and specificity of stool Ag were 100 and 91 respectively  Conclusion  Stool Ag test has high sensitivity and negatity predictive value for diagnosis of Helicobacter pylori infection.

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 03 Oct 2017 17:59
Last Modified: 03 Oct 2017 17:59
URI: http://eprints.mums.ac.ir/id/eprint/7478

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