Aseptic Meningitis after MMR Vaccination in Children of Mashhad

Sasan, Mohammad Saeed and Haji Shamsaei, Mahboube (2010) Aseptic Meningitis after MMR Vaccination in Children of Mashhad. medical journal of mashhad university of medical sciences, 53 (3). pp. 163-168.

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Abstract

Introduction In Iran vaccination against Mumps (with Zagreb strain) has been started since 2005, and since that time the incidence of Mumps and its complications (like meningitis) has dramatically decreased. However during the 3 years after Mumps vaccination there have been frequent reports of Parotitis and Meningitis in the first few weeks after the shot. This article is the report of the authors experience about the probable adverse reactions of mumps vaccine. Materials and Methods This was prospective cross sectional observational study in Pediatric wards of Imam Reza and Dr Sheikh hospitals from August 2004 up to July 2009. In this study children who developed Parotitis or Meningitis within 0ne to six weeks after MMR vaccination were considered as probable Mumps vaccine adverse reaction. Results There were 24 cases of Meningitis (with or without Parotitis) and 16 cases of isolated Parotitis during 9 to 39 days after MMR vaccination. Male to Female ratio was 3/1 in Meningitis and 2/3 in Parotitis group. In the whole group 65 (26 ) of children were 4-6 years old and 30 of them (12 cases) were One year old, and in all of them this was the first shot of Mumps vaccine. We had a probable case of vaccine virus transmission from a 7 years old girl to her 14 years old brother. Conclusion Meningitis is a common event during one to six weeks after Mumps vaccination with the current (Zagreb) strain.

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 03 Oct 2017 18:00
Last Modified: 03 Oct 2017 18:00
URI: http://eprints.mums.ac.ir/id/eprint/7479

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