Comparison of Dexamethazone and Ondansetron with Dexamethazone and Metoclopramidein preventation of post � operative nausea and vomiting

Sahabi, Seyyed Mehdi and Alereza, Hakimeh and Alijanpore, Ebrahim and Banihashem, Nadia and Hassannasab, Bahman and Seify, Safoura (2010) Comparison of Dexamethazone and Ondansetron with Dexamethazone and Metoclopramidein preventation of post � operative nausea and vomiting. medical journal of mashhad university of medical sciences, 53 (2). pp. 73-78.

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Abstract

Introduction Positive effectiveness of antiemetic drugs was approved in reduction of post-operative nauseaand vomiting) PONV. The purpose of this study was comparison of Dexamethazone and Ondansetron with Dexamethazone and Metoclopramide in preventation of PONV. Materials and Methods In this study, was selected 80 women in ASA class I, II for elective abdominal hysterectomy under general anaesthesia and was divided in to two groups (n= 40). One group received a combination of Dexamethazone with Ondansetron and in second group was injected a combination of Dexamethasone with Metoclopramide near the end of surgery. PONV was evaluated at 2hr and 6 hr after operation. The results were analyzed, using pearson chi-square and fisher�s exact test. Results Injection of two drugsOndansetron and Metoclopramide affect in reduction PONV. But, the rate of reduction of nausea and vomiting was not significant in 2 groups in 2 hr after surgery (p= 0.723). Its rate was significantly lower in Ondansetron group after 6 hr (p< 0/001). Conclusion In the patients with selective hysterectomy under general anesthesia for reduction of PONV can be apply from acombination of Dexamethasone and Ondansetron which show more effectiveness and longer duration as compared to Metoclopramide and Dexamethasone

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 03 Oct 2017 18:16
Last Modified: 03 Oct 2017 18:16
URI: http://eprints.mums.ac.ir/id/eprint/7497

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