Peripartum cardiomyopathy (A literature review)

Vakilian, Farveh and Tara, Fateme and Moosavi, Fateme (2014) Peripartum cardiomyopathy (A literature review). Reviews in Clinical Medicine, 1 (4). pp. 194-199.

RCM_Volume 1_Issue 4_Pages 194-199.pdf

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Heart failure (HF) is a serious and growing public health concern, which has many causes. Pregnancy is a critical condition with significant hemodynamic and immunologic changes. Peripartum cardiomyopathy (PPCM) is a disease of unknown cause in which left ventricular (LV) dysfunction occurs during the last trimester of pregnancy or the early puerperium. PPCM is known to be the most common cardiovascular cause of severe complications in pregnancy. Risk factors for peripartum cardiomyopathy include advanced maternal age, twin pregnancy, smoking, pregnancy-related hypertension and preeclampsia, multiparity, African descent, and long-term tocolysis. Oxidative stress and some inflammatory markers have been diagnosed in PPCM pathophysiology. Recent observations have suggested that bromocriptine might favor recovery of LV systolic function in patients with PPCM. Patients developed peripartum cardiomiopathy treated with bromocriptine showed significantly improved LV ejection fraction and heart failure symptoms. This article tries to have a short review on this clinical scenario.

Item Type: Article
Subjects: WG Cardiovascular System
WP Gynecology
Divisions: Journals > Reviews in Clinical Medicine
Depositing User: RCM RCM
Date Deposited: 05 Oct 2017 15:09
Last Modified: 05 Oct 2017 15:09

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