A Case Report of Extramedullary Hematopoiesis in Sphenoidal Sinus in Patient with Intermediate Beta Thalassemia and Review of Literature

Mozaheb, Zahra (2009) A Case Report of Extramedullary Hematopoiesis in Sphenoidal Sinus in Patient with Intermediate Beta Thalassemia and Review of Literature. medical journal of mashhad university of medical sciences, 52 (3). pp. 186-191.

[img]
Preview
Text
MJMS_Volume 52_Issue 3_Pages 186-191.pdf

Download (615kB) | Preview
Official URL: http://mjms.mums.ac.ir/article_5435.html

Abstract

Introduction Extramedullary hematopoiesis is an important side effect of intermediate thalassemia. It is usually observed in paravertebral and other soft tissues as a compressive mass and rarely in intracranial, but it has not been roported in sphenoidal sinus in literature until now. Case report In this article a 21- year old patient with intermediate thalassemia and sphenoidal mass has been reported. The patient underwent splenectomy and cholecystectomy simultaneously, for the billiary stones. After splenectomy his erythroblast increasesd progressively in peripheral blood, and one year later he was treated, because of acute sinusitis. Imaging studies and biopsy revealed the hematopoietic mass in sphenoidal sinus. The patient did not respond to surgical and medical treatments; therefore, he was referred for the hematopoietic stem cell transplantation. Conclusion Ectopic hematopoiesis is a rare event in thalassemia, but it can appear in such important areas such as paravertebral and intracranial, which causes severe side effects. Therefore, immediate diagnosis and treatment in high risk patients can prevent these effects.

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 05 Oct 2017 14:19
Last Modified: 05 Oct 2017 14:19
URI: http://eprints.mums.ac.ir/id/eprint/7661

Actions (login required)

View Item View Item