Evaluation of Visual Evoked Potentials� Findings in Patients with Multiple Sclerosis

Froughipoor, Mohsen and Khosravi, Alireza and Saedi, Morteza and Koranian, Faranak (2008) Evaluation of Visual Evoked Potentials� Findings in Patients with Multiple Sclerosis. medical journal of mashhad university of medical sciences, 51 (4). pp. 203-208.

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Abstract

Introduction Multiple Sclerosis is one of the commonest neurological disorders that because of its different clinical presentation, recurrent and progressive attacks, and age spectrum of patients who are usually young, has particular importance. Optic neuritis is common in MS patients and VEP is abnormal in most of the patients with optic neuritis. VEP is also abnormal in most of the MS patients who do not have the history of optic neuritis. The aim of this study was to compare the incidence of VEP in MS patients with and without the history of optic neuritis. Materials and Methods This study included 80 patients with definite MS diagnosis who referred to the MS Clinic Ghaem Hospital. A questionnaire used to collect the patients demographic and illness history. Patients were divided into two groups based on the history of optic neuritis. The full neurological examination including VEP carried out for the patients. Collected data analyzed with SPSS and statistical tests. Results The abnormal VEP found in 92.2 of patients with the history of optic neuritis. The incidence of VEP in patients without the history of optic neuritis was 57.5. The VEP abnormality recorded 40.5 unilateral and 59.5 bilateral in the first group of patients. In the second group the VEP was 87 unilateral and 13 bilateral. Conclusion Many MS patients without the history of optic neuritis, had abnormal VEP, therefore VEP can be used for the early diagnosis of MS. Although, patients with the history of optic neuritis will have significant improvement with the time, but many cases with increased P100 latency is persistence, and can be used as a marker of the pervious optic neuritis attack.

Item Type: Article
Subjects: WA Public Health
Divisions: Journals > Medical J Mashhad University of Medical Sciences
Depositing User: mjmums mjmums
Date Deposited: 05 Oct 2017 15:34
Last Modified: 05 Oct 2017 15:34
URI: http://eprints.mums.ac.ir/id/eprint/7701

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