The effects of whole green tea infusion on mouse urinary bladder chemical carcinogenesis

Henriques, Andreia and Arantes-Rodrigues, Regina and Faustino-Rocha, Ana I and Teixeira-Guedes, Catarina I and Pinho-Oliveira, Jacinta and Talhada, Daniela and Teixeira, José H and Andrade, Andreia and Colaço, Bruno and Paiva-Cardoso, Maria N and Pires, Maria J and MVD Ferreira, Ana and Nunes, Fernando M and Oliveira, Paula A (2014) The effects of whole green tea infusion on mouse urinary bladder chemical carcinogenesis. Iranian Journal of Basic Medical Sciences, 17 (2). pp. 145-148.

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Abstract

Objective(s):Green tea (GT) is one of the most popular beverages worldwide whose beneficial effects on health have been demonstrated. Recent studies suggest that GT may contribute to reduction of cancer risk and progression. The aim of this study was to evaluate the effects of whole GT on urinary bladder chemical carcinogenesis in male and female ICR mice. Materials and Methods: The GT characterization was performed using spectrophotometric methods. Urinary bladder lesions were induced using N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) by gavage during 10 weeks and whole GT (0.5) was provided ad libitum during 20 weeks. Results:Animals from groups BBN+GT and BBN only developed preneoplastic lesions. Conclusion:We did not observe any effects by GT infusion administration on urinary bladder cancer development.

Item Type: Article
Subjects: QV pharmacology
Divisions: Journals > Iranian J Basic Medical Sciences
Depositing User: ijbms ijbms
Date Deposited: 08 Oct 2017 16:11
Last Modified: 08 Oct 2017 16:11
URI: http://eprints.mums.ac.ir/id/eprint/8036

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