Vasculitic peripheral neuropathy

Amini, Mona and Boostani, Reza and Sahebari, Maryam (2014) Vasculitic peripheral neuropathy. Reviews in Clinical Medicine, 1 (1). pp. 25-28.

RCM_Volume 1_Issue 1_Pages 25-28.pdf

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Primary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 of patients have peripheral nervous system (PNS) involvement. In vasculitic peripheral neuropathies (VPN) a necrotizing and inflammatory process leads to narrowing of vasa nervorum lumen and eventually the appearance of ischemic lesions in peripheral nerves. Some features might be suggestive of VPN, like: axonal nerve degeneration, wallerian-like degeneration, and diameter irregularity of nerve. Peripheral nervous system (PNS) destruction during systemic vasculitides should be considered, due to its frequency and early occurrence in vasculitis progression. The first line treatment of non systematic VPNs is corticosteroid agents, but these drugs might worsen the VPNs or systemic vasculitis.

Item Type: Article
Subjects: WL Nervous system
Divisions: Journals > Reviews in Clinical Medicine
Depositing User: RCM RCM
Date Deposited: 08 Oct 2017 17:06
Last Modified: 08 Oct 2017 17:06

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