Prevalence of PER-1- type Extended-Spectrum Beta-Lactamaes in Clinical Strains of Pseudomonas aeruginosa Isolated from Tabriz, Iran

Akhi, Mohammad Taghi and Khalili, Yones and Ghottaslou, Reza and Aghazadeh, Mohammad and Seroush Bar Haghi, Mohammad hosein and Yousefi, Saber (2012) Prevalence of PER-1- type Extended-Spectrum Beta-Lactamaes in Clinical Strains of Pseudomonas aeruginosa Isolated from Tabriz, Iran. Iranian Journal of Basic Medical Sciences, 15 (1). pp. 678-682.

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Abstract

Objective(s) The aim of this study was to investigate the presence of PER-1-type ESBLs in drug resistant Pseudomonas aeruginosa isolates. Materials and Methods During one-year period (2008-2009), following isolation and identification of 56 P. aeruginosa, the E-test method was performed for determination of minimal inhibitory concentration of ceftazidim. The isolates that they had MIC≥16 µg/ml against ceftazidim were used for determination of ESBL-producing by combined disk test (CDT) and double disk synergy test (DDST) methods. Bla PER-1genewas investigated by PCR.P. aeruginosa KOAS was used as positive control. Results Twenty-nine (51.78) out of fifty six isolates had MIC≥16 µg/ml to ceftazidime, twenty two (75.86) of them were ESBL producers. Some isolates (27.5) contained bla PER-1 gene. Conclusion PER-1-type ESBLs producing P.aeruginosa has not been reported previously in Tabriz but there has been a rather high prevalence of it.

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Journals > Iranian J Basic Medical Sciences
Depositing User: ijbms ijbms
Date Deposited: 06 Nov 2017 18:17
Last Modified: 06 Nov 2017 18:17
URI: http://eprints.mums.ac.ir/id/eprint/8528

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