Assessment of Ultrasound / Radio-guided Occult Lesion Localization in Non-palpable Breast Lesions

Alamdaran, Seyed Ali and Sharifi Haddad, Ayda and Daghighi, Navid and Modoodi, Elaheh and Sadeghi, Ramin and Forghani, Mohammad Naser and Fattahi, Asieh Sadat (2018) Assessment of Ultrasound / Radio-guided Occult Lesion Localization in Non-palpable Breast Lesions. Asia Oceania Journal of Nuclear Medicine and Biology, 6 (1). pp. 10-14.

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Objective(s): Controversy exists about the localization of non-palpable breast lesions. In many countries, the gold standard for the diagnosis of these lesions is needle localization due to its accuracy. This study sought to compare the ultrasoundand radio-guided occult lesion localization (ROLL) as a simple method with the conventional procedures in terms of their diagnostic power. Methods: This study was conducted on 94 patients with non-palpable breast lesions detected by ultrasonography and localized by the combination of ultrasonography and using radiopharmaceuticals. One to ten hours prior to surgery, 0.1-0.2 ml (equivalent to 0.5-1 mCi) of Tc-99m-phytate was injected to the lesion under the guidance of ultrasonography. Then, the lesion was localized using a hand-held gamma probe, and excision of the lesion was performed according to its radioactivity signal. Data analysis was performed using SPSS, version 16. Results: Benign and malignant pathologic results were observed in 77 (81.9) and 17(18.1) of the patients, respectively, and the mean volume of the excised tissue was 26.29±27 mm³. 79 patients had a solitary lesion (84), 55 in the left breast (58.5) and 39 in superolateral quadrant (41.5). The mean size of the lesions was 15.7 mm in diameter (ranging from 4 to 34 mm). Additionally, there was a need to secondary surgery in 3 (3.2) patients and inappropriate localization in 6 (6.4) patients (subcutaneous or intra-ductal spread of radiodrug). Conclusion: Combination of ultrasound- and radio-guided localization methods for localizing non-palpable breast lesions is a simple and acceptable method for localization with no significant complications. For radio-drug spread and subsequent excessive excised tissue volume, subcutaneous and intra-ductal lesions are not suitable indication for ROLL.

Item Type: Article
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Journals > Asia Oceania J Nuclear Medicine & Biology
Depositing User: AOJNMB AOJNMB
Date Deposited: 28 Dec 2017 15:04
Last Modified: 29 Dec 2017 01:36

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