Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review

Ayoobi, Fatemeh and Shamsizadeh, Ali and Fatemi, Iman and Vakilian, Alireza and Allahtavakoli, Mohammad and Hassanshahi, Gholamhossein and Moghadam-Ahmadi, Amir (2017) Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review. Iranian Journal of Basic Medical Sciences, 20 (6). pp. 604-612.

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Abstract

The Achillea millefolium L. (Yarrow) is a common herb which is widely being used, worldwide. Achillea is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in Achillea. Most of both antioxidant and anti-inflammatory properties of this herb have been attributed to its flavonoid content. Oxidative and inflammatory processes play important roles in pathogenesis of neurodegenerative diseases. Present review was aimed to review the latest literature evidences regarding application of Achillea and/or its three main flavonoid constituents on epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and stroke.

Item Type: Article
Subjects: QT physiology
Divisions: Journals > Iranian J Basic Medical Sciences
Depositing User: ijbms ijbms
Date Deposited: 22 Sep 2017 19:11
Last Modified: 22 Sep 2017 19:11
URI: http://eprints.mums.ac.ir/id/eprint/923

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