Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method

Kaveh, Fatemeh and Amini, Kumarss and Sadeh, Mojtaba (2018) Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method. The Iranian Journal of Obstetrics, Gynecology and Infertility, 21 (3). pp. 39-44.

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Abstract

Introduction: Breast cancer is a common malignancy and a major cause of death in women. Viruses are considered as one of the risk factors associated with breast cancer. Herpes simplex virus-1 (HSV-1) and HSV-2 are involved in the pathogenesis of cancer. The present study was conducted to determine the frequency of HSV-1 and HSV-2 in the blood samples of patients with breast cancer using multiplex-polymerase chain reaction (M-PCR) technique. methods: This cross-sectional study was conducted on 60 breast cancer patients within 2014-2015. The infection with HSV-1 and HSV-2 was investigated by M-PCR. All data were analyzed using SPSS software (version 18). Results: Out of the 60 blood samples obtained from patients with breast cancer, 6 (10) and 3 (5) samples were positive for HSV-1 and HSV-2, respectively. Conclusion: herpes simplex virus, especially HSV-1, can play a role as a cofactor in the incidence of breast cancer, so further studies are recommended in this area.

Item Type: Article
Subjects: WP Gynecology
WQ Obstetrics
Divisions: Journals > Iranian J Obstetrics, Gynecology and Infertility
Depositing User: ijogi ijogi
Date Deposited: 21 Jun 2018 05:23
Last Modified: 21 Jun 2018 05:23
URI: http://eprints.mums.ac.ir/id/eprint/9825

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